Stearic Fatty Acid in Adipose Tissue in Some Pathologic Conditions United with Preterm Atherosclerosis

In the paper the findings of investigations of the percentage of content of stearic fatty acids in adipose tissue from 250 persons are presented, containing different disturbances and having very often as consequence a preterm development of atherosclerosis. The results are compared with a control group (n = 93) of metabolic healthy and normally nourished persons. The method of gas-liquid chromatography is used. Except for persons with an phenotype picture of hyperlipoproteinemia type IIa, in all persons (obese, NIDDM, sudden death from myocardial infarction, other types of hyperlipoproteinemia) significant lower values of stearic fatty acids compared to the control group (p<0.005-0.001) are determined and a significant connection of its decrease with the degree of nourishedness. (r = 0.662, p<0.001) in obese persons is also discovered. In opposition to that, undernourished persons had some higher value of stearic fat acids statistically insignificant. The results are completely in accordance with our earlier findings in separate lipid fractions in serum and in serum in general. The fact that some other authors who invesigated the problem have come to identical results points to the conclusion that our investigations represent the confirmation of a new knowledge about the antiatherogenic effect of the fatty acids in contrast with other long chain saturated fatty acids. No doubt, these findings have certain implications on treatment of patients as well.